This course is co-directed by the University of Minnesota and the Karolinska Institute in Stockholm, Sweden and is taught by a team of more than 20 internationally recognized experts. It will be valuable for academic and industrial scientists and health care professionals with an interest in pain research and/or treatment.
Topics include the neurobiology of pain transmission, the pathophysiology of chronic pain, human and animal models of chronic pain, translational pain research, common human pain syndromes and current information on treatment options and outcomes.
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Monday June 1 - Basic Science
8:00 Bagels and Coffee
8:30 Welcome and Introductions (Wilcox)
8:40 Why study pain, scale of the problem (Elde)
9:00 Cellular Neurobiology (Elde)
9:30 Nociceptors, Nociception & Pain I (Honda)
10:15 Coffee Break
10:45 Nociceptors, Nociception & Pain II (Honda)
11:45 Gender and Pain (Beitz)
12:30-2:00 Lunch (provided)
2:00 Human Psychophysics Lab (Simone)
3:00 Structure and Function of Nociceptive Pathways (Giesler)
4:00 Peripheral & Central Sensitization (Seybold)
5:00 Q&A / Roundtable (Wilcox, Honda, Seybold)
5:30 Close
6:00 Opening Reception at Campus Club
Tuesday June 2: AM - Preclinal
8:00 Bagels and Coffee
8:30-10:15 Laboratory: Human Anatomy (C. Honda)
10:15 Coffee Break
10:30 Sensory Assessment in Animals (Fairbanks)
11:30-1:00 Lunch on your own
1:00 Experimental Pharmacology (Brodin)
2:00 Analgesic Neuropharmacology (Svensson)
2:30 Coffee Break
3:00 Genomics (Fairbanks)
3:30 Proteomics (Vulchanova)
4:00 DISCUSSION: Experimental Modeling of Pain (Fairbanks, Meyerson)
5:00 Q&A / Roundtable (Brodin, Fairbanks, Svensson, Meyerson)
5:30 Close
Wednesday June 3
AM - Analgesia and Antihyperalgesia
8:00 Bagels and Coffee
8:30 Descending Inhibitory and Facilitatory Systems (Wessendorf)
9:30 Peripheral and Central Targets for analgesics (Wilcox)
10:30 Coffee Break
11:00 Synergistic Pharmacology (Fairbanks/Wilcox)
12:00-1:30 Lunch (provided)
PM Part 2: Pain Assessment in Humans
1:30 Assessing Pain in Humans (Walk)
2:00 Assessing Pain in Nonverbal Human Populations (Symons)
2:30 Psychological Aspects of Pain Management (Olaughlin)
3:00 Coffee Break
3:30 Functional Imaging of Pain (Alonso)
4:00 Surgical Interventions for Pain (Meyerson)
5:00 Q&A / Roundtable (Wessendorf, Walk, Wilcox, Meyerson, OLaughlin, Symons)
5:30 Close
Thursday June 4 – Chronic Pain Synromes
8:00 Bagels and Coffee
8:30 General Principles of Chronic Pain Treatment (Segerdahl)
9:00 Inflammation/Arthritis (Svensson)
9:30 Neuropathic Pain (Walk, Segerdahl)
10:15 Coffee Break
10:30 Cancer Pain (Wilcox, Simone, Seybold)
11:00-12:30 Lunch on your own
12:30 Orofacial Pain (Kopp)
1:00 Low Back Pain (Anderson)
1:30 Visceral Pain (Vulchanova)
2:00 Muscle Pain (Larson)
2:30 Coffee Break
3:00 Fibromyalgia (Larson)
3:30 Migraine (Kopp)
4:00 Trigeminal Pain Mechanisms (Bereiter)
4:30 Trigeminal Neuralgia (Nixdorf)
5:00 Q&A / Roundtable (Nixdorf, Segerdahl, Meyerson, Vulchanova)
5:30 Close
Friday June 5
AM – Integration of Basic and Clinical
8:00 Bagels and Coffee
8:30 Neuroimmune Mechanisms UnderlyinPain (Beitz, Larson)
10:00 Coffee Break
10:30 TENS/Acupuncture Panel Basic Research and Clinical Applications (Fairbanks, Beitz, Belgrade, Flores)
12:00-1:30 Lunch (provided)
PM Part 2: Control of Pain at the Spinal Cord Level
1:30 Spinal Modulation of Pain (Fairbanks)
2:00 Spinal Cord Stimulation (Meyerson)
2:30 Intrathecal Chronic Infusion (Charry)
3:00 Coffee Break
3:30 Round Table (with patients or case studies)
4:30 Closing Comments
4:45-5:45 Course Exam
Classes will be held in the Molecular and Cellular Biology Building (MCB) Room 3-120. Located on Washington Ave (420 Washington Ave, Minneapolis, MN 55455) between Harvard and Church Streets. Campus maps and directions are available at http://www1.umn.edu/pts/maps.htm.
There will be a “Welcome Reception” on Monday June 1, 5-9 p.m. and will be held at the Campus Club Roof Top Terrace and Lounge, located on the 4th floor of Coffman Memorial Union. A Dinner Reception will be held on Thursday June 4, (5 – 9 p.m.) at the Loring Pasta Bar in Dinkytown. Prior RSVP is required for both of these events.
We recommend parking in the Washington Avenue Ramp, (511 Washington Avenue S.E. Minneapolis, MN 55455) which is attached to the Radisson Metrodome hotel and within a two blocks of MCB, Coffman Union and the Alumni Center. Parking is hourly with a maximum of $12/day. If full, we suggest the East River Road Ramp under Coffman Memorial Union as a backup (see http://www1.umn.edu/pts/maps.htm)
